Phenothiazinium photosensitisers XI. Improved toluidine blue photoantimicrobials
نویسندگان
چکیده
منابع مشابه
Phenothiazinium photoantimicrobials with basic side chains.
Derivatives of the standard cationic photosensitiser, methylene blue, were synthesised, having extra amino (basic) functionality in the auxochromic side-chain. The resulting analogues were profiled for photodynamic activity in vitro, and screened against standard Gram-positive and Gram-negative bacteria for photobactericidal activity. The substitution pattern of the derivatives was such that io...
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Phenothiazine-based photosensitisers have been employed in photoantimicrobial research for nearly 80 years, both as lead and novel compounds. However, the main structural variations have mainly involved the auxochromic side chains and little has been reported concerning either peripheral substitution or structures with chromophores other than those of the phenothiazinium or annelated benzo[a]ph...
متن کاملPhotosensitization of T2 coliphage with toluidine blue.
The photodynamic action of dyes upon biological systems has been reviewed by Blum (1941). Inactivation of bacteriophage by this process has been studied by Clifton (1931), Perdrau and Todd (1933), Burnet (1933), Morales (1941), and Pacheco and Morales (1941). More recently, Welsh and Adams (1954) and Yamamoto (1956, 1958) investigated the kinetics of photodynamic inactivation of coliphage. In t...
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Our improved toluidine blue-DNA agar was compared with methyl green DNase test agar for the detection of DNA hydrolysis by campylobacters. The toluidine blue-DNA agar gave clear-cut positive and negative reactions with campylobacter strains belonging to several species.
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Serratia marcescens was isolated on a new medium-commercial deoxyribonuclease agar with the addition of cephalothin (1,000 mug/ml) and Toluidine Blue (1,000 mug/ml). It was detected in water samples even though it comprised only 0.1 to 0.0001% of the total bacterial population.
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ژورنال
عنوان ژورنال: Journal of Photochemistry and Photobiology B: Biology
سال: 2016
ISSN: 1011-1344
DOI: 10.1016/j.jphotobiol.2016.03.035